When is dying?

When is Sirt1 activity bad for dying neurons?

Sirt1, the class III histone deacetylase, is generally associated with increased life span and with a pro-survival effect in neurons stressed by pathological factors. Recent work, however, suggests that Sirt1 silencing could also promote neuronal survival. A possible reason suggested is Sirt1 silencing enhanced expression of both IGF-1 and IGF-1 receptor, signaling from which promotes survival....

When every $P$-flat ideal is flat

In this paper‎, ‎we study the class of rings in which every $P$-flat‎ ‎ideal is flat and which will be called $PFF$-rings‎. ‎In particular‎, ‎Von Neumann regular rings‎, ‎hereditary rings‎, ‎semi-hereditary ring‎, ‎PID and arithmetical rings are examples of $PFF$-rings‎. ‎In the context domain‎, ‎this notion coincide with‎ ‎Pr"{u}fer domain‎. ‎We provide necessary and sufficient conditions for‎...

Dying is a transition.

PURPOSE End-of-life care is designed as response to patients' verbally communicated needs. The concept of dying as a process would allow us to improve care. This concept may combine the needs of the dying, their outburst of emotions, gradual maturation, family processes, acute problems such as decreasing independence, with their inner experience and transformation of perception. In this study w...

when appropriate statistical analysis is dismissed

Is P2P dying or just hiding?

Recent reports in the popular media suggest a significant decrease in peer-to-peer (P2P) file-sharing traffic, attributed to the public’s response to legal threats. Have we reached the end of the P2P revolution? In pursuit of legitimate data to verify this hypothesis, we embark on a more accurate measurement effort of P2P traffic at the link level. In contrast to previous efforts we introduce t...